Although increasing incidence of infections with methicillin-resistant Staphylococcus
aureus(MRSA) has been reported in other countries, the situation of our country is not
clearly ascertained.
S. aureus isolated from various clinical specimens at Yonsei Medical Center was
tested for the antimicrobial susceptibility by the Kirby-Bauer method. The MRSA
isolated in 1981 was tested for the antimicrobial susceptibility by agar dilution method.
Following results were obtained.
1) Increased prevalence of MRSA from 0% to 31.7% was noted during the period of
August 1979 to June 1982.
2) MRSA was isolated only from inpatients but not from outpatients. No difference
was noted in the isolation rate by sources of specimen.
3) Cephalothin was the most active drug against MRSA, showing the lowest LlIC
range, MICSO and MICSO. Among the MRSA isolates, 91.2% was susceptible to this
drug.
4) To amikacin, 58.8% of the MRSA was susceptible while all were resistant to
dibekacin, gentamicin, tobramycin.
It is concluded from this study that infections due to MRSA is increasing among
inpatients, and increasing difficulty is anticipated to control MRSA infection as the
amikacin is the only active aminoglycoside.
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